PVA Brain Phantom Images

Simulated data

We have created an anatomically and mechanically realistic brain phantom from polyvinyl alcohol cryogel (PVA-C) for validation of image processing methods for segmentation, reconstruction, registration, and denoising. PVA-C is material widely used in medical imaging phantoms for its mechanical similarities to soft tissues. The phantom was cast in a mold designed using the left hemiphere of the Colin27 brain dataset and contains deep sulci, a complete insular region, and an anatomically accurate left ventricle. Marker spheres were also implanted to enable good registration. Inflatable catheters were used to simulate tissue deformations. 

Colin27 moldPVA phantom


Multi-modality imaging

The phantom was designed for triple modality imaging, giving good contrast images in computed tomography, ultrasound, and magnetic resonance imaging. Imaging data from each modality, and from multiple deformation level, were acquired. This page contains images files of the PVA Brain phantom. For each deformation instant, you can download one pack that archives reconstructed and unreconstructed B-mode ultrasound (US) images at 5.2cm and 7.1cm depth, as well as reformatted MR and CT volumes. These images are made freely available to the image processing community.

Here is an example that you can download (about 13 Mo): With no deformation at all, a first ultrasound volume was acquired (7.1cm depth, Superior Frontal). MR and CT volumes have been cropped to fit in this US volume's space.
First line, from left to right: MR T1, CT registered rigidly to MR
Second line, from left to right: Cropped MR, cropped CT and US volume.
The cropped MR and CT were resliced according to the transformation of the neuronavigation system. Therefore, the volumes are roughly aligned and not perfectly registered.
Entire MR T1 Entire CT


Reconstructed volumes

All  volumes are stored in NIFTI (.nii) format. Download this 5 volume example on the download page (13M).

Simulated deformations

Deformations were created as injected liquid volumes increase in the two catheters. For each deformation instant, the phantom was imaged with CT, MR and ultrasound.
4 inflations in T1

For each instant, a image archive containing all images can be downloaded. Here is the content of each archive:

- "MR-CT" contains the MR and CT images. The MR sequence contains a 3D T1, Flair, T2 and Diffusion weighted sequence.

- "US" contains the acquired ultrasound slices, with different field of view. For each sequence, the raw data in stradx format (http://mi.eng.cam.ac.uk/~rwp/stradx/stradx_files.html) are provided, as well as the reconstructed volumes in nifty format using the distance weighted interpolation. For each acquisition, a transformation matrix (.mat) is also provided that matches the US coordinate system to those of the "preoperative" MR image.

- "US_denoised" contains the denoised version of the reconstructed US volumes using the NL-means method.

- "MR_cropped" and "CT_cropped" contain the resliced MR and CT volume for each US acquisition. The cropped MR and CT were resliced according to the transformation of the neuronavigation system. Therefore, the volumes are roughly aligned and not perfectly registered. The transformation stored in file US.mat describes the transformation matrix that was used to reslice the MR according to the FOV of the US. The transformation was used as an input of the VTKReslice class.

Catheter 1 Catheter 2 MR,CT and US Images
0ml 0ml All US, cropped MR and cropped CT volumes (around 200M)
5ml 0ml All US, cropped MR and cropped CT volumes (around 200M)
5ml 5ml All US, cropped MR and cropped CT volumes (around 200M)
5ml 10ml All US, cropped MR and cropped CT volumes (around 200M)
10ml 10ml All US, cropped MR and cropped CT volumes (around 200M)



Displacement images

The following are the images scanned with displacements. Ten of the scans are done with the phantom submerged in water while the other 10 are done without.
Water Scans
With
Displacement T1 3D Gradient echo
1 Compressed nifti
2 Compressed nifti
3 Compressed nifti
4 Compressed nifti
5 Compressed nifti
6 Compressed nifti
7 Compressed nifti
8 Compressed nifti
9 Compressed nifti
10 Compressed nifti
Without
Displacement T1 3D Gradient echo
1 Compressed nifti
2 Compressed nifti
3 Compressed nifti
4 Compressed nifti
5 Compressed nifti
6 Compressed nifti
7 Compressed nifti
8 Compressed nifti
9 Compressed nifti
10 Compressed nifti

All the displacement images can also be download as single archive here (740M).


Reference and contacts


If you use these images please cite :

Sean Jy-Shyang Chen, Pierre Hellier, Jean-Yves Gauvrit, Maud Marchal, Xavier Morandi, and D. Louis Collins (2010) An Anthropomorphic Polyvinyl Alcohol Triple-Modality Brain Phantom based on Colin27, MICCAI 2010

Contacts

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